In this episode, Dr. Gillian Lockitch welcomes Dr. Anna Sitkoff for a fascinating discussion on medicinal mushrooms and their role in promoting healthy aging. Listeners will learn how mushrooms support brain function, mood, cortisol balance, immune health, and longevity. From shiitake and oyster mushrooms to reishi and lion’s mane, Anna explains the science behind these ancient remedies and shares practical tips for integrating culinary and medicinal mushrooms into your daily routine.
Dr. Anna Sitkoff is a licensed naturopathic doctor and medicinal mushroom expert with over a decade of experience blending clinical practice with hands-on laboratory research. She is the co-founder and Chief Science Officer of Lucidum Medicinals, where she formulates evidence-based mushroom supplements designed to support immune, lung, and nervous system health. Internationally recognized for her expertise in functional medicine, women’s health, and herbalism, Dr. Sitkoff is passionate about empowering patients and practitioners with natural, science-based therapies and recipes that fit into everyday life.
Episode Timeline
[00:00] – Guest introduction and welcome to the podcast
[05:24] – Anna’s early influences, family health challenges, and discovery of medicinal mushrooms
[08:29] – Journey through naturopathic school, laboratory cancer research, and starting her mushroom supplement company
[12:29] – What defines a mushroom, the role of mycelium, and why substrate matters for bioactive compounds
[17:00] – Culinary vs. medicinal mushrooms: oyster, shiitake, maitake, and the common white mushroom
[19:52] – Ergothioneine and its neuroprotective role in aging and mitochondrial health
[25:10] – Reishi: the “mushroom of immortality,” immune benefits, and bone broth extractions
[30:08] – Lion’s Mane, nerve growth factor, BDNF, mood, memory, and cognitive protection
[34:09] – Practical tips for daily mushroom use: cooking, extracts, powders, and broths
[35:40] – Wrap-up, gratitude, and where to connect with Dr. Sitkoff
Download your complimentary Guide from Dr. Lockitch
Quick Guide to Medicinal and Culinary Mushrooms
Learn about Dr. Sitkoff and medicinal mushrooms
Instagram @drannasitkoff
Connect with Dr. Gillian Lockitch
Email: askdrgill@gmail.com
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